Broader questions of hazard are sometimes poorly understood.

Many chemistry research institutions do not investigate chemicals for hazard in its broadest sense. Knowledge of toxicity and hazard is fragmented across institutions and sectors.  This is true in both the agricultural and industrial chemical sectors, in academic, industrial and government labs.

For example, the USDA has several research labs across the United States that focus on discovering new pesticide products which are sourced from nature. The typical process is that the USDA does the basic research and, when promising chemicals are identified, USDA licenses them to universities or industry for further research into the applications of the chemical. But USDA does not investigate whether or not the chemicals they license are hazardous to human health and the environment.

There are missing skills sets in the product discovery and development process. Broader questions of human and ecological health – both for the active ingredient and the inert ingredients in which the active ingredient is suspended – often are not systematically addressed.

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